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| Saleem,Afia; Bukhari,Syed Majid; Zaidi,Asma; Farooq,Umar; Ali,Majid; Khan,Asma; Khan,Sidra; Shah,Kausar Hussain; Mahmood,Adeem; Khan,Farhan Ahmed. |
| The 4-Hydroxycoumarin derivatives are known to show a broad spectrum of pharmacological applications. In this paper we are reporting the synthesis of a new series of 4-Hydroxycoumarin derivatives synthesized through Knovenegal condensation; they were characterized by using UV-Vis, FT-IR, NMR spectroscopies. The synthesized compounds were evaluated for antibacterial activity against Staphylococcus aureus and Salmonella typhimurium strains. The compounds (2), (3) and (8) showed favorable antibacterial activity with zone of inhibitions 26.5± 0.84, 26.0 ± 0.56 and 26.0 ± 0.26 against Staphylococcus aureus (Gram-positive) respectively. However, the compounds (5) and (9) were found more active with 19.5 ± 0.59 and 19.5 ± 0.32 zone of inhibitions against... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 4-Hydroxycoumarin; Anti-urease; Carbonic anhydrase; Aldehydes; Antibacterial. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100580 |
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| Taşkın,Turgut; Gezmiş,Tuğba; Çam,Muhammet Emin; Taşkın,Duygu; Çelik,Berna Özbek; Şenkardeş,İsmail; Süzgeç-Selçuk,Sevda. |
| In Turkey, Helichrysum genus is represented by 26 taxa belonging to 20 species in Turkish flora of which 14 ones are endemic to Turkey. The aerial parts of Helichrysum plicatum subsp. plicatum are used kidney stones, kidney and stomach ailments. The extraction procedures and solvents are important step in processing of bioactive constituents from the plant materials. Therefore, the aim of this study was to evaluate in vitro antioxidant, antimicrobial, anti-urease, anticholinesterase and in vivo anti-inflammatory activities of Helichrysum plicatum subsp. plicatum different extracts. In addition, the phenolic characterization of the Soxhlet and maceration methanol extracts which showed significant antioxidant, anti-urease, antimicrobial, anti-inflammatory... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Helichrysum plicatum subsp; Plicatum; Anti-inflammatory; Anti-urease; Anticholinesterase; HPLC-DAD-MS. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100554 |
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